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br RNA was extracted from whole cell
2020-08-28
RNA was extracted from whole cell lysates and reverse transcribed to cDNA using a reverse-transcriptional kit (TaKaRa). RT-PCR was performed in a triplicate with the SYBR Prime Script RT-PCR kit (TaKaRa) on the Step One Plus Real-Time PCR system (Applied Biosystems). The sequences are described in
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96036-03-2 br Based on initial results we formed a working g
2020-08-28
Based on initial results, we formed a working group of cli-nicians from RPCI and clinicians, cancer registrars, and administrative staffs from LLC who discussed and determined what additional parameters were relevant in the context of the 96036-03-2 we were assessing. Once the parameters to be
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br miR a mimic miR a inhibitor
2020-08-28
miR-34a mimic, miR-34a inhibitor, control mimic and control in-hibitor were transfected using Lipofectamine 2000 (Invitrogen, Carlsbad, CA, USA) according to the manufacturer's instructions. PC-3 SYBR Safe DNA Gel Stain were seeded into dishes using medium with 10% FBS and no pe-nicillin/streptom
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br Authors br Luca Cantini Mirco Pistelli Filippo
2020-08-18
Authors Luca Cantini1, Mirco Pistelli1, Filippo Merloni1, Andrea Fontana2, Ilaria Bertolini2, Claudia De Angelis2, Lucia Bastianelli1, Arianna Della Mora1, Alfredo Santinelli3, Agnese Savini1, Elena Maccaroni1, Lucrezia Diodati2, Alfredo Falcone2, Rossana Berardi1 1Clinica Oncologica, Univer
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br the hypothesis that GLuc A sr TK
2020-08-18
the hypothesis that GLuc-2A-sr39TK can be used as a precision diagnostic platform for minute human PDAC. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.) localization of PDAC, we performed transient transfection of
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br Modulating the Tumor Microenvironment
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3.3 Modulating the Tumor Microenvironment Spontaneous tumors are comprised of many cell populations including tumor cells, immune 878557-19-8 (both immune-stimulating and immunosuppressive populations), fibroblasts, and endothelial cells in addition to acellular components. These are collectiv
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br New Zealand like many other
2020-08-18
New Zealand like many other countries has a national Cancer Registry, which is based on clinical and pathological data for all pa-tients diagnosed with a first invasive cancer. Such registration is routine and legally protected and there is no requirement for consent. As a result the registry can
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br Fig Molecular mechanism of autophagy
2020-08-18
Fig. 1. Molecular mechanism of autophagy regulation in mammals. Autophagic process consists of several phases such as initiation (A), nucleation (B), maturation (C), fusion and degradation (D). Same colours express the involvement of proteins or molecules in respective complexes or pathways.
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br Supplementary data br Cieza
2020-08-18
Supplementary data 11. Cieza A, Geyh S, Chatterji S, Kostanjsek N, Ustun BT, Stucki G: Identification of candidate categories of the Inter-national Classification of Functioning Disability and Health (ICF) for a Generic ICF Core Set based on regression model-ling. BMC Med Res Methodol 6:36, 200
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br Background br Aging is associated with decreased physiolo
2020-08-14
1. Background Aging is associated with decreased physiologic reserve, comorbidity and polypharmacy, functional dependence, and inadequate social sup-port [1–4]. The rate and amount of change varies from individual to in-dividual, but some level of comorbidity is present in N90% of patients with
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br We included all female patients
2020-08-14
We included all female patients with a primary diagnosis of breast cancer admitted and discharged from US hospitals between January 1st, 2007 and December 31st, 2014 represented in the NIS. Males and pa-tients younger than 18 years were excluded (n = 170,644) (Supplemental Fig. 1). Inpatient stays
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br Materials and methods We
2020-08-12
Materials and methods: We queried the National Cancer Database and identified 27,170 patients who underwent radical cystectomy with urinary diversion from 2004 to 2013. Patient demographics, socioeconomic variables, and hospital-related factors were compared between incontinent and continent dive
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AM251 International Journal of Pharmaceutics br Conclusions
2020-08-12
International Journal of Pharmaceutics 568 (2019) 118511 4. Conclusions Herein we reported a non-covalent conjugation approach between AT11 and AT11-B0 G4 and acridine orange derivatives in order to promote their selective delivery into HeLa cervical cancer cells. The resulting complexes we
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br MODEL br ARHGEF as a
2020-08-12
+ MODEL ARHGEF38 as a novel biomarker 7 cancers except breast cancer in the United States. In addition, the analysis of RNA-seq PRAD data from the TCGA dataset indicated that ARHGEF38 is significantly upregu-lated in PCa compared to normal prostate tissue and the ARHGEF38 Calpain Inhibitor I
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br previously described protocol and the success of the
2020-08-12
previously described protocol and the success of the iodination reaction was monitored by using SEC-ICP-MS. The chromatogram corresponding to the iodinated antibody is shown in Fig. 2. The iodine trace is shown in Fig. 2A and the sulfur trace in Fig. 2B (acquired in low and medium resolution respe